A confrontation between the agent and the car's occupants led to gunfire. It was unclear how many shots were fired by the agent. The Secret Service said there is no evidence that anyone was harmed.
The suspects fled the scene in the sedan, and a lookout was issued to local law enforcement, Guglielmi said.
The D.C. Metropolitan Police Department is investigating the shooting and the case will also be reviewed by the U.S. Attorney’s Office.